Nutritional Stress as an adverse effect of anti-diabetic medications

Abstract

Objective: To estimate the intensity of nutritional stress among the diabetic patients. Background: Non-Communicable diseases (NCDs) are the leading cause of morbidity and mortality in Pakistan. The WHO report evaluated diabetes at the fourth position among the four types of NCD’s, this accounts for 1.5 million deaths annually. Nutritional stress depends on what we give to our body, whether it is toxin loaded, chemically constituted platefuls of food and expect it to cope without a grumble. As, diabetes is metabolic syndrome so there is an altered carbohydrate and fat metabolism in these patients that will lead to the development of nutritional stress in these patients. Methodology: A cross sectional survey based study was conducted at a local hospital including diabetic patients on anti-diabetic medicines. Demographic data, medical history and drug use duration and dosage were investigated as well as intensity of nutritional stress was calculated by Sadaf stress scale (SSS). The patients with severe and psychological and mental illness or any other chronic illness or patients who were failed to provide reliable information were excluded from study. Result: The total of 42 patients have participated in the study out of that 50% have reported mild nutritional stress and 36% have reported moderate nutritional stress. The most common reported symptom of nutritional stress includes sleep problem, abdominal bloating, incomplete emptying and sugars and carb craving. Conclusion: The patients have reported the nutritional stress due to the altered carbohydrate and fat metabolism and the use of anti-diabetic medicine further increases the intensity of nutritional stress. The symptoms that are reported in diabetic patients are not associated with diabetes instead occur as a result of anti-diabetic medication use. Such as, sleep problem usually associated with increased stress, increased blood pressure, impaired control of blood glucose, and increased inflammation.