Leiomyosarcoma of the Superficial Femoral vein – A rare tumor at an unusual site.

  • Javaria Aleem Shaukat Khanum Memorial Cancer Hospital and Research Centre, Pakistan.
  • Pir Abdul Ahad Aziz Qureshi Syed Abdullah Shah Institute of Medical Sciences, Pakistan. https://orcid.org/0000-0002-3620-4940
  • Kashif Siddique Shaukat Khanum Memorial Cancer Hospital and Research Centre, Pakistan.
  • Amna Babar Shaukat Khanum Memorial Cancer Hospital and Research Center, Pakistan.
Keywords: Leiomyosarcoma, Vascular Leiomyosarcoma, Vascular Tumor, Lung Metastases, Metastatic Vascular Leiomyosarcoma.


Background: The leiomyosarcomas most commonly arise from smooth muscles of the uterus and gastrointestinal tract. The vascular origin of the leiomyosarcoma is very rare; however, veins are more frequently affected in such cases.

Case Presentation: A 23-year-old boy presents with left thigh painless swelling. Subsequently, he underwent multimodality radiological examinations, which showed left superficial femoral vein mass, which later on histopathological evaluation came out to be grade III leiomyosarcoma of the superficial femoral vein.

Management & Results: The patient was given chemotherapy, but unfortunately, after three cycles of chemotherapy patient developed pulmonary metastases. Currently, the patient is under palliative treatment.

Conclusion: Primary vascular leiomyosarcomas are very rare entities. The knowledge of these rare tumors is essential for the reporting radiologists and clinicians to properly diagnose these aggressive tumors to prevent any delays in the management.


Download data is not yet available.


1. Kransdorf MJ. Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location. AJR Am J Roentgenol 1995; 164 (1): 129-134.
2. Sephien A, Mousa MS, Bui MM, Kedar R, Thomas K. Leiomyosarcoma of the inferior vena cava with hepatic and pulmonary metastases: case report. J Radiol Case Rep 2019; 13(5): 30–40.
3. Stramare R, Orsatti G, Attar S, Rastrelli M, Brunello A. Imaging Features, Differential Diagnosis and Management of Leiomyosarcomas: Case Series and Review of the Literature. J Cancer Sci Ther. 2016; 8: 084-091.
4. Shindo S, Katsu M, Kaga S, Inoue H, Ogata K, Matsumoto M. Leiomyosarcoma of a femoral vein misdiagnosed as deep vein thrombosis. J VascInterv Radiol 2009; 20(5): 689-691.
5. Roy AD, Deka M, Dutta UC. Vascular leiomyosarcoma of thigh – A rare tumour at an unusual site. Australas Med J 2013; 6(10): 520–523.
How to Cite
Aleem, J., Qureshi, P. A. A. A., Siddique, K., & Babar, A. (2021). Leiomyosarcoma of the Superficial Femoral vein – A rare tumor at an unusual site. International Journal of Endorsing Health Science Research (IJEHSR), 9(4). Retrieved from http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/763